Neuramis Deep Lidocaine 1-Needle
$25
Neuramis Deep Lidocaine (1 Needle) — Medytox SHAPE™ HA Filler for Deep Wrinkles
What it is
Neuramis Deep Lidocaine (1-needle version) is the medium-density tier of Medytox’s SHAPE™ dermal filler range — designed for nasolabial folds, marionette lines, forehead wrinkles, and lip augmentation. The SHAPE™ 2-step cross-linking process delivers natural integration with residual BDDE below 0.4 PPM. This 1-needle pack includes a single 27G UTW (Ultra Thin Wall) needle.
How SHAPE™ Technology works
SHAPE™ (Stabilized Hyaluronic Acid & Purification Enhancement) is Medytox’s patented manufacturing process used across the Neuramis range. Two engineering decisions distinguish it from standard BDDE cross-linking:
Traditional process: BDDE and HA react in a single step. Result: significant unreacted BDDE remains, requiring extensive post-purification.
SHAPE process: A first cross-linking reaction is followed by a second cross-linking pass on the under-reacted HA chains. More BDDE is consumed in reactions; less is left as residue. The gel network is also denser and more stable, contributing to longer in-vivo duration.
Multiple dialysis cycles remove any remaining unreacted BDDE before final sterilization, followed by additional pre-sterilization purification.
Result: residual BDDE < 0.4 PPM — five times stricter than the EU regulatory ceiling of < 2 PPM. Endotoxin levels also held to ultra-low specification.
| Cross-linking technology | Manufacturer | Core mechanism | Residual BDDE |
|---|---|---|---|
| SHAPE™ (this product) | Medytox (Korea) | 2-step cross-linking + enhanced purification | < 0.4 PPM |
| NASHA® | Galderma (Sweden) | Biphasic particle cross-linking | Industry standard |
| Vycross® | Allergan (USA) | High + low MW HA blend cross-linking | Industry standard |
| CPM® | Merz (Germany) | Polydensified cohesive matrix | Industry standard |
| Hy-BRID | GENOSS (Korea) | Uniform-particle HA | Industry standard |
EU MDR ceiling for residual BDDE in dermal fillers is < 2 PPM. SHAPE™ operates 5× stricter than the regulatory floor. Comparison based on manufacturer-published technical data.
Lower residual BDDE reduces the risk of inflammatory and hypersensitivity reactions. Denser cross-linking from the 2-step process extends in-vivo durability. Medytox is also the manufacturer of Neuronox botulinum toxin — the same Korean GMP infrastructure produces the Neuramis range.
Technical specifications
Detail for clinical, regulatory, and shipping reference. Headline figures shown in the panel above.
| Pack Configuration | 1 syringe + 1 needle (economy pack) |
| Needle Type | 27G ½” UTW (Ultra Thin Wall) |
| BDDE Residue | <0.4 PPM |
| HA Source | Bacterial fermentation, non-animal origin |
| Cross-linking | SHAPE™ 2-step process + enhanced purification |
| Manufacturer | Medytox Inc. |
| Origin | South Korea |
| Certifications | CE marked · KFDA · GMP certified |
| Storage | 2–25 °C · do not freeze · protect from direct sunlight |
| Shelf life | 24 months unopened (verify lot label) |
| Reversibility | Dissolvable with hyaluronidase if needed |
| Intended use | Licensed medical professionals only |
FAQ
When should I choose Neuramis Deep over Volume?+
Both use Medytox SHAPE™ technology and 20 mg/mL HA + 0.3% lidocaine, but differ by viscoelasticity. Deep (medium density) — nasolabial folds, marionettes, deep wrinkles, lip body, forehead lines (9–12 month duration). Volume (high density) — cheek augmentation, chin projection, nose contouring (12–18 month duration). Choose Deep for wrinkle correction; Volume for structural facial volume.
How long does this product last?+
Duration is 9–12 months depending on injection site, patient metabolism, and lifestyle. Mobile facial zones (lips, perioral) typically resorb faster than static zones (cheek, temple). Individual hyaluronidase activity also influences longevity.
What’s the storage requirement?+
Standard HA filler storage at 2–25 °C (room temperature acceptable). Do not freeze. Protect from direct sunlight. No cold-chain shipping required (this is not a botulinum toxin). 24-month shelf life unopened; verify lot label before use.
Where to buy wholesale and how to verify authenticity?+
Wholesale through MJS Medicals for licensed healthcare professionals. To verify authenticity: (1) intact tamper-evident sterile seal; (2) batch number with manufacturer traceability label; (3) HA concentration matches 20 mg/mL on packaging; (4) Korean origin marking visible; (5) CE / KFDA certification visible on box.
Who is qualified to inject?+
Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with HA filler-specific training only. Buyers self-certify professional status at checkout.
Safety
This product-specific: Mid-to-deep dermal placement near nasolabial and perioral facial artery branches. Aspirate before injection; cannula technique recommended in vascular zones. The 27G UTW needle provides larger inner diameter for smoother flow.
Prescription medical device. Contraindicated in known hypersensitivity to HA, lidocaine, or Gram-positive bacterial proteins; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune disorders; active local infection; and concurrent anticoagulant therapy. Aspirate before injection; keep hyaluronidase on hand for reversal.
→ Full Dermal Filler Safety Information
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