Xeomin 100U Korean Version
$156
Xeomin 100U is Merz Pharma’s purified botulinum toxin type A, distinguished by a complexing-protein-free formulation that carries only the active 150 kDa neurotoxin. The vials offered here are the genuine Merz product routed through Korea’s authorized pharmaceutical wholesale channel — English-labeled and identical in formulation to the US and EU supply.
Why practitioners reach for Xeomin
In its natural state, botulinum toxin type A travels as a roughly 900 kDa complex: the working 150 kDa neurotoxin wrapped in about 750 kDa of haemagglutinin and non-toxic accessory proteins. Those accessory proteins add nothing therapeutically — the neurotoxin dissociates and acts on the nerve terminal on its own at physiological pH. Merz’s purification removes that surrounding protein load entirely, so each Xeomin vial delivers the pure neurotoxin and little else.
The clinical rationale is immunological: foreign accessory proteins are one of the inputs the immune system can use to build neutralizing antibodies over years of repeat treatment. By stripping them out, Xeomin aims to keep long-term responders responding. In practice it has become a common choice for patients who have developed reduced response to other toxins, and Merz reports no confirmed cases of antibody-mediated resistance to Xeomin to date.
Clinical indications
Approved and commonly treated uses include:
- Aesthetic: glabellar (frown) lines, horizontal forehead lines, and lateral canthal lines (crow’s feet).
- Therapeutic: cervical dystonia, blepharospasm, upper-limb spasticity, and chronic sialorrhea (excessive drooling).
- Resistant patients: a practical option where antibody response to another botulinum product is suspected.
Handling & reconstitution
Reconstitute with sterile, preservative-free 0.9% saline and handle gently. Store the vial refrigerated at 2–8 °C, protect it from light, and do not freeze. Excipients are human serum albumin and sucrose. As with any botulinum product, potency units are specific to Xeomin and are not interchangeable unit-for-unit with other brands.
About the Korean-import route
“Korean-imported version” refers only to the supply channel, not the product itself. These are authentic Merz-manufactured vials from Frankfurt that entered Korea’s licensed pharmaceutical wholesale system and are redistributed with English labeling. The route generally prices below direct US/EU distribution while the formulation remains identical to Xeomin sold in those markets.
Frequently asked questions
Is the “Korean version” the same product as Western Xeomin?
Yes. It is genuine Xeomin made by Merz in Germany; only the distribution path differs. The neurotoxin, potency, and formulation match the US/EU product.
What does “complexing-protein-free” actually mean?
It means the accessory proteins that normally surround the neurotoxin have been removed during manufacturing, leaving essentially just the active 150 kDa toxin — the basis for Xeomin’s lower theoretical immunogenicity.
Can I switch a resistant patient to Xeomin unit-for-unit?
Dosing should follow Xeomin’s own labeling and your clinical judgment; units are not directly interchangeable between botulinum products.
Safety
Botulinum toxin type A is a prescription medical product for licensed practitioners only. It is contraindicated in neuromuscular junction disorders, at sites of active infection, and in pregnancy or breastfeeding. Rare distant spread of toxin effect has been reported — keep emergency airway support available and counsel patients accordingly.
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