Manla Kar
$46
Manla Kar — Korean Atelocollagen Skin Booster for Skin Regeneration
Manla Kar is an atelocollagen skin booster, not an HA dermal filler. It is supplied as a 1 mL liquid concentrate that requires dilution with sterile saline before injection (not reconstitution of a powder — Manla Kar is already a liquid). Application is via multi-injection or microneedle technique for skin regeneration, not single-point volume placement.
What it is
Manla Kar is a Korean medical-grade collagen skin booster containing high-purity atelocollagen — collagen extracted from porcine (pig) skin with the antigenic telopeptide component enzymatically removed. The result is a collagen molecule structurally close to human collagen (~99.9% biocompatibility) with minimal immune-rejection risk. Applied via multi-injection or microneedle technique after saline dilution, Manla Kar stimulates fibroblast activity and supports skin regeneration, elasticity, and texture improvement.
How atelocollagen works
Native porcine collagen contains telopeptide regions that can trigger immune responses in human tissue. Atelocollagen production uses enzymatic digestion to remove these telopeptide regions, leaving only the non-antigenic triple-helical structure. When injected into skin, atelocollagen acts as both an immediate biostimulator (supplementing depleted collagen) and a long-term scaffold for the patient’s own fibroblasts to deposit new endogenous collagen — producing gradual, natural-looking skin regeneration over 4–12 weeks post-treatment.
Clinical application — 3 scenarios
Manla Kar usage varies by treatment goal and zone. Below are the three established protocols from manufacturer documentation.
Goal: Tissue supplementation, elasticity restoration
Dilution: None — use pure
Needle: 30G or 32G
Depth: Mid dermis (1.2–2.4 mm)
Dose: 0.05–0.1 mL per linear cm, multiple injection points
Goal: Dark circles, periorbital fine lines
Dilution: 1 mL Manla Kar + 1 mL sterile 0.9% saline (1:1 ratio)
Device: 4 mm microneedle device (MTS / dermastamp)
Technique: Topical application + microneedle pass
Aftercare: Cold compress 5–10 min
Goal: Full-face skin regeneration, texture, hydration
Dilution: 1 mL Manla Kar + 1 mL saline + 1 mL HA skin booster (1:1:1 ratio)
Compatible boosters: Saypha Rich, Restylane Skinboosters, Profhilo, Juvelook
Technique: Mesotherapy gun or multi-point superficial dermal injection
- Patient face cleansing → topical anesthetic applied 20–30 min before treatment (no premixed lidocaine in product)
- Prepare sterile drape, disinfect treatment zone
- Withdraw 1 mL Manla Kar + saline (and skin booster if Scenario C) into sterile mixing syringe
- Mix by gentle inversion or light swirling — do NOT shake vigorously (shear forces denature the collagen triple helix)
- Use diluted solution within 6 hours at room temperature, or 24 hours refrigerated 2–8 °C
- Inject per scenario protocol above
- Post-treatment: cold compress, no makeup for 24 h, no exercise / sauna 48 h
Manla Kar works through collagen biostimulation — results develop gradually over weeks, not hours. Standard course:
- Session interval: 2–4 weeks between treatments
- Initial course: 3–4 sessions for full effect
- Maintenance: 1 session every 6–12 months
- Visible result onset: 4–12 weeks post-session (endogenous collagen production)
Technical specifications
Detail for clinical, regulatory, and shipping reference.
| Active Ingredient | High-purity atelocollagen (telopeptide-free) |
| Collagen Source | Porcine (pig skin), ~99.9% homology to human collagen |
| Pack Size | 1 × 1.0 mL liquid concentrate (not powder) |
| Dilution Protocol | Saline 1:1 (eye area) or saline + skin booster 1:1:1 (face) |
| Application Technique | Multi-point injection (30G/32G) or 4 mm microneedle device |
| Injection Depth | Mid dermis (1.2–2.4 mm) for direct injection |
| Primary Indications | Skin regeneration, elasticity, dark circles, skin texture refinement |
| Mechanism | Immediate biostimulation + long-term fibroblast scaffolding |
| Treatment Course | 3–4 sessions at 2–4 week intervals, then 6–12 month maintenance |
| Diluted Solution Stability | 6 hours at room temp, 24 hours at 2–8 °C; do not re-use |
| Lidocaine | Not included (apply topical anesthetic 20–30 min pre-treatment) |
| Manufacturer | CMK Global / Starpharmtec (verify per lot label) |
| Origin | South Korea |
| Storage (unopened) | 2–25 °C · do not freeze · protect from direct sunlight |
| Shelf life | 24 months unopened (verify lot label) |
| Intended use | Licensed medical professionals only |
FAQ
How is Manla Kar different from a regular HA dermal filler?+
Manla Kar is not a dermal filler — it is an atelocollagen skin booster. Standard HA fillers (Juvederm, Neuramis, Monalisa, etc.) add volume via cross-linked HA gel placed in a single point as a ready-to-use syringe. Manla Kar is applied diffusely via multi-injection or microneedle technique to stimulate the patient’s own collagen production, and it requires saline dilution before injection — it is not a ready-to-use syringe.
Is it dilution or reconstitution?+
Strictly speaking it is dilution — Manla Kar is supplied as a 1 mL liquid concentrate, not a freeze-dried powder. Practitioners mix the liquid with sterile saline in the syringe before injection. “Reconstitution” in pharmaceutical usage refers to dissolving a lyophilized powder; that term is technically incorrect for Manla Kar even though some clinics use the words interchangeably.
Why use atelocollagen instead of native collagen?+
Native animal-source collagen contains telopeptide regions that can trigger immune rejection in human tissue. Atelocollagen production uses enzymes to remove these telopeptides, leaving only the non-antigenic triple-helix collagen molecule. The result is a collagen ~99.9% homologous to human collagen with minimal immune-rejection risk — safer for clinical use than native porcine or bovine collagen.
How is Manla Kar prepared and applied?+
There are 3 standard application scenarios. (1) Direct subdermal injection: use Manla Kar undiluted with 30G/32G needle for tissue supplementation. (2) Eye area / dark circles: dilute 1:1 with sterile 0.9% saline, apply via 4 mm microneedle device. (3) Skin booster combo: dilute 1:1:1 with saline + HA skin booster product, apply via mesotherapy gun or multi-point superficial injection. All scenarios require gentle mixing (no vigorous shaking — shear denatures collagen), topical anesthetic pre-treatment, and use of diluted solution within 6 hours.
How many sessions do I need?+
Manla Kar is a course-based treatment, not a one-and-done filler. Standard protocol: 3–4 sessions at 2–4 week intervals for the initial course, then 1 maintenance session every 6–12 months. Visible improvement develops gradually over 4–12 weeks post-session as endogenous collagen production responds to biostimulation — this is fundamentally different from HA fillers which show immediate volume change.
How long do results last?+
Visible skin quality improvement typically maintains for 12–18 months after a complete 3–4 session course. Patient skin metabolism, age, and lifestyle significantly influence longevity. Maintenance sessions every 6–12 months sustain the cumulative effect.
Where to buy wholesale and how to verify authenticity?+
Wholesale through MJS Medicals for licensed healthcare professionals. To verify authenticity: (1) Manla Kar branding with “Dimlo Collagen” sub-label on packaging; (2) Korean origin marking; (3) intact tamper-evident sterile seal; (4) batch number with manufacturer traceability label; (5) clear / transparent liquid solution appearance (not powder).
Who is qualified to apply?+
Licensed physicians, dermatologists, plastic surgeons, and aesthetic practitioners with skin booster / mesotherapy training only. Dilution requires sterile technique. Buyers self-certify professional status at checkout.
Safety
This product-specific: Porcine-source atelocollagen — verify no patient hypersensitivity to porcine proteins before use. Multi-injection technique increases needle entry points; aseptic preparation and treatment-site decontamination critical. Dilution must use sterile 0.9% saline only; mix by gentle inversion (no vigorous shaking — shear forces denature the collagen triple helix); use diluted solution within 6 hours at room temperature.
Prescription medical device. Contraindicated in known hypersensitivity to porcine collagen; severe allergies / anaphylaxis history; pregnancy / breastfeeding; autoimmune collagen disorders (e.g. lupus, scleroderma); active skin infection at treatment site; bleeding disorders or concurrent anticoagulant therapy. Dilution + multi-injection technique requires advanced skin booster / mesotherapy training.
→ Full Skin Booster Safety Information
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