Botulax 100ui
$40
Botulax 100U — Hugel
What it is
Botulax 100U is Hugel Pharma’s flagship botulinum toxin type A — Korea’s most distributed botulinum brand with a 22-country export footprint. Each vial contains 100 units of Clostridium botulinum toxin type A (, Hugel’s proprietary working strain) purified via size-exclusion HPLC to with 0.5 mg human serum albumin and 0.9 mg sodium chloride. Its active ingredient (letibotulinumtoxinA) is FDA-approved in the US under the separate brand Letybo (2024).
What makes it distinctive
Botulax’s primary advantage is the rare combination of established Korean market leadership (Korea’s #1 botulinum brand by share) with its active ingredient’s FDA approval as Letybo. The and allowing direct dose translation between products.
Approved & off-label indications
Technical specifications
Detail for clinical, regulatory, and shipping reference.
| Active Ingredient | Clostridium botulinum toxin type A |
| Strain | Ltd. (KOSDAQ 145020) |
| Origin | Chuncheon, South Korea |
| Approvals | MFDS (KFDA) approved · Active (letibotulinumtoxinA) its active is FDA-approved as Letybo (2024). Botulax brand is not US-approved. |
| Onset / Duration | 3–7 days onset · 4–6 months duration |
| Reconstitution | Sterile preservative-free 0.9% saline |
| Storage | Store at 2–8 °C, protect from light, do not freeze. |
| Reconstituted shelf life | 24 hours at 2–8 °C |
| Shelf life (unopened) | 36 months from manufacture |
| Intended use | Licensed medical professionals only |
Frequently Asked Questions
allowing direct dose translation between the two products.
The Botulax brand itself is not FDA-approved. However, its active ingredient (letibotulinumtoxinA) is FDA-approved in the US under the separate brand Letybo (2024). Botulax is MFDS (KFDA) approved in South Korea.
Both products use the 900 kDa molecular complex, making units directly translatable — clinicians can substitute Botulax 1:1 for Allergan Botox in dosing protocols. The Hall strain used by Allergan and the used by Hugel both produce 150 kDa neurotoxin cores within a 900 kDa complex. Clinical efficacy is comparable in head-to-head trials; pricing is significantly lower than Allergan, which reflects Korean manufacturing economics rather than potency differences.
Duration is typically 4–6 months depending on injection site, dose, and individual patient metabolism. Onset begins 3–7 days post-injection with peak effect at approximately 14 days. Mobile facial zones (lips, perioral) typically resorb faster than static zones (forehead, glabella).
Store unopened vials at 2–8 °C refrigerated. Do not freeze. Reconstitute with sterile preservative-free 0.9% saline — typically 2.5 mL for 4U/0.1 mL dilution. Gently swirl to dissolve (do not shake, which can denature the protein). Use reconstituted solution within 24 hours, kept refrigerated.
Hugel was the second Korean botulinum company to launch (after Medytox), and Botulax achieved Korean market leadership through KFDA approval longevity, aggressive pricing, and extensive clinician relationships. Botulax holds the largest market share among Korean botulinum products domestically, with Nabota at approximately 32% in second place.
Look for: (1) Hugel branding and KOSDAQ 145020 reference on outer carton; (2) batch number matching between box and vial; (3) intact tamper-evident vial seal; (4) visible white lyophilized powder cake in the vial bottom; (5) MFDS (KFDA) approval reference where labeling space permits.
Related Products
Other botulinum toxin products from MJS Medicals — different manufacturers, formulations, and price points.
Botulax 200U
Same Hugel at 200-unit pack — cost-efficient for high-volume practices.
View product →
Botulax 300U
Hugel’s 300-unit pack (2024 launch) — lowest per-unit cost for sustained high-volume use.
View product →
Nabota 100U
Daewoong’s HI-PURE™ vacuum-dried formulation — US FDA approved as Jeuveau.
View product →
Liztox 100U
BioPure Extraction at purity — low-immunogenicity Korean alternative.
View product →
Browse all botulinum toxin products at MJS Medicals.
Safety
This product-specific: Botulax 100U carries the same class-wide botulinum toxin warnings as all Type A products including potential distant toxin spread, neuromuscular junction disorder contraindications, and pregnancy/lactation contraindication. Always aspirate before injection; maintain emergency airway management equipment.
Botulinum toxin Type A is a prescription medical product for licensed healthcare professionals only. Contraindicated in neuromuscular junction disorders (myasthenia gravis, Lambert-Eaton, ALS); known hypersensitivity to botulinum toxin or excipients; pregnancy / breastfeeding; active local infection; concurrent aminoglycoside / anticholinesterase / curare-like drugs. Class-wide warning: rare distant toxin spread possible (symptoms hours-to-weeks post-injection). Maintain emergency airway management equipment and epinephrine.
→ Full Botulinum Toxin Safety Information
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