Sculptra

$378

SKU: 100266 Category:
Sculptra · PLLA · Collagen Stimulator
Sculptra PLLA
Poly-L-Lactic Acid · Collagen Biostimulator

Sculptra is a poly-L-lactic acid (PLLA) collagen biostimulator supplied as a lyophilized powder for reconstitution. Rather than adding gel volume, its PLLA microparticles trigger a controlled response that stimulates the skin’s own collagen gradually over a series of treatments, for natural-looking restoration of facial volume that develops over months.

PLLA Collagen Stimulator · Lyophilized · Reconstituted with Sterile Water
Overview

How Sculptra works

Sculptra is a pure biostimulator: it does not fill directly but prompts the body to rebuild collagen. After reconstitution and injection, the PLLA microparticles cause a controlled, subclinical response that drives gradual collagen synthesis. Because the result depends on new collagen, it develops progressively across a series of sessions for a subtle, natural outcome.

Composition

What’s in Sculptra

POLY-L-LACTIC ACID (PLLA)150 mg · microparticlesBiostimulator

PLLA microparticles, 150 mg per vial.

Poly-L-lactic acid is a synthetic, biocompatible, resorbable polymer. Its microparticles stimulate fibroblasts to produce new collagen over time, then biodegrade and clear from the body.

LYOPHILIZED POWDER367.5 mg freeze-driedFormat

Freeze-dried preparation, 367.5 mg per vial.

Each vial contains 367.5 mg of freeze-dried powder, including 150 mg of PLLA, reconstituted before use.

RECONSTITUTED BEFORE USESterile waterPreparation

Reconstituted with sterile water.

Sculptra is reconstituted with sterile water for injection before use, agitated thoroughly until evenly suspended; lidocaine may be added per the clinical protocol.

Protocol

Reconstitution & treatment

Reconstitution
Reconstitute with sterile water for injection per the instructions for use; agitate thoroughly until evenly suspended. Lidocaine may be added per protocol.
Sessions
Administered as a series of treatments spaced several weeks apart, set by the practitioner based on the area and degree of correction.
Injection
Injected into the deep dermis / subcutaneous layer by a licensed practitioner, followed by massage as directed.
Onset
Results build gradually as new collagen forms over weeks to months across the treatment series.
Indications

Treatment focus

Nasolabial folds and facial wrinkles
Facial volume loss and lipoatrophy
Cheek and temple volume
Skin firmness and elasticity
Gradual, natural-looking restoration
Collagen-based rejuvenation
Specifications

Specifications

Product
Sculptra
Brand
Sculptra
Active
Poly-L-lactic acid (PLLA) microparticles
Composition
150 mg PLLA per vial
Presentation
367.5 mg freeze-dried powder × 1 vial
Preparation
Reconstitute with sterile water for injection
Protocol
Series of treatments, weeks apart
Injection
Deep dermis / subcutaneous
Mechanism
Gradual collagen biostimulation
Duration
Long-lasting, builds over the series
Manufacturer
Galderma
Regulatory
US FDA approved (PMA P030050)
Category
Collagen stimulator
Use
Single use — licensed practitioners only
FAQ

Frequently asked questions

What is Sculptra?

A poly-L-lactic acid (PLLA) collagen biostimulator supplied as a lyophilized powder. It is reconstituted with sterile water and injected to stimulate the skin’s own collagen over a series of treatments.

How is Sculptra different from a filler?

It does not add gel volume directly; the PLLA stimulates new collagen gradually, so the result develops over months and across several sessions for a natural look.

Is Sculptra FDA approved?

Yes. Sculptra is approved by the US FDA (PMA P030050) for aesthetic indications, manufactured by Galderma.

How is Sculptra reconstituted?

With sterile water for injection per the instructions for use, agitated thoroughly until evenly suspended; lidocaine may be added per the clinical protocol.

How many treatments are needed?

Sculptra is given as a series of treatments spaced several weeks apart; the practitioner determines the number based on the area and goals.

When will results show?

Because results come from new collagen, they build gradually over weeks to months rather than appearing immediately.

How long do results last?

Sculptra provides long-lasting, gradual restoration that builds across the treatment series and is maintained as collagen is stimulated.

Who can administer Sculptra?

Licensed, trained practitioners only — reconstitution and injection technique require appropriate training.

Related

Related collagen stimulators

Radiesse
Calcium Hydroxylapatite · Dual-Action Biostimulator
Rejubella
Polydioxanone Microspheres · Collagen Biostimulator
Ultra Ca+
Calcium Hydroxylapatite · Dual-Action Biostimulator
All Collagen Stimulators
Browse the full range.
Safety

Safety information

Sculptra is approved by the US FDA (PMA P030050) for aesthetic indications. This product is a collagen stimulator for licensed practitioners only. It must be prepared and injected at the appropriate depth using aseptic technique. Do not treat over active infection or inflammation, and avoid in pregnancy and breastfeeding or in patients with known hypersensitivity to the product components. As with all collagen biostimulators, delayed nodules or foreign-body reactions are possible; correct preparation, injection plane and technique help reduce this risk. Refer to the manufacturer’s instructions for use before treatment.

Sculptra is a trademark of its respective brand owner. For licensed healthcare professionals only. Last reviewed: June 2026.

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