Radiesse

$205

SKU: 100227 Category:
Radiesse · CaHA · Collagen Stimulator
Radiesse CaHA
Calcium Hydroxylapatite · Dual-Action Biostimulator

Radiesse is a calcium hydroxylapatite (CaHA) dermal filler and collagen biostimulator. CaHA microspheres suspended in a carboxymethylcellulose gel carrier give immediate volume on injection, while the microspheres stimulate the skin’s own collagen over time. Supplied ready to use, it provides both instant correction and gradual, collagen-based rejuvenation that can last well over a year.

CaHA Microspheres + CMC Gel · Ready to Use · Immediate Volume + Collagen
Overview

How Radiesse works

Radiesse is a dual-action regenerative filler. The carrier gel provides immediate, 1:1 volume correction and structural support; as it is gradually resorbed, the CaHA microspheres remain at the site and act as a scaffold that stimulates new collagen and elastin. This combination of instant volume and long-term biostimulation is what distinguishes Radiesse from simple gel fillers.

Composition

What’s in Radiesse

CALCIUM HYDROXYLAPATITE (CaHA)30% · microspheresBiostimulator

CaHA microspheres, ~25–45 µm.

Calcium hydroxylapatite microspheres — a mineral-like substance also found naturally in the body — act as a scaffold that stimulates new collagen and elastin, then biodegrade and are resorbed over time.

CMC GEL CARRIER70% · immediate volumeCarrier

Carboxymethylcellulose gel.

The carboxymethylcellulose carrier gel evenly distributes the microspheres and provides immediate 1:1 volume correction, then gradually dissipates, leaving the CaHA at the injection site.

READY TO USEPrefilled · dual actionPreparation

Prefilled, no reconstitution.

Radiesse is supplied ready to use — no reconstitution required. It can be mixed with lidocaine per the approved protocol for added comfort if desired.

Protocol

Preparation & treatment

Preparation
Ready to use — supplied prefilled; no reconstitution. May be mixed with lidocaine per the approved protocol if desired.
Injection
Injected into the subdermal / deep dermal plane by a licensed practitioner for volume and contour.
Onset
Immediate volume from the carrier gel; collagen-based results build over the following months as the CaHA stimulates new collagen and elastin.
Duration
Results can persist for up to around 30 months as collagen turnover continues.
Indications

Treatment focus

Nasolabial folds and marionette lines
Jawline and chin contour
Cheek and midface volume
Hand rejuvenation
Skin firmness and elasticity
Immediate volume + long-term collagen
Specifications

Specifications

Product
Radiesse
Brand
Radiesse
Active
Calcium hydroxylapatite (CaHA) microspheres
Carrier
Carboxymethylcellulose gel
Composition
30% CaHA microspheres + 70% CMC gel
Particle size
~25–45 µm
Preparation
Ready to use — no reconstitution
Injection
Subdermal / deep dermal
Mechanism
Immediate volume + CaHA collagen stimulation
Duration
Up to ~30 months
Manufacturer
Merz Aesthetics
Regulatory
US FDA approved (PMA P050052)
Category
Collagen stimulator
Use
Single use — licensed practitioners only
FAQ

Frequently asked questions

What is Radiesse made of?

Calcium hydroxylapatite (CaHA) microspheres — about 30% — suspended in a carboxymethylcellulose gel carrier (about 70%), giving immediate volume plus long-term collagen stimulation.

How does Radiesse work?

The carrier gel provides immediate volume; as it resorbs, the CaHA microspheres act as a scaffold that stimulates new collagen and elastin for gradual, longer-term improvement.

Is Radiesse FDA approved?

Yes. Radiesse is approved by the US FDA (PMA P050052) for aesthetic indications, manufactured by Merz Aesthetics.

Does Radiesse need reconstitution?

No. It is a ready-to-use prefilled product; it can be mixed with lidocaine per the approved protocol for comfort if desired.

How long do results last?

Up to around 30 months, combining immediate volume with sustained collagen stimulation.

Where is Radiesse used?

Areas such as the nasolabial folds, jawline, chin, cheeks and hands, by a licensed practitioner.

Is Radiesse a collagen stimulator or a filler?

Both — it provides immediate volume like a filler and stimulates collagen like a biostimulator, a dual mechanism unique among common fillers.

Who can administer Radiesse?

Licensed, trained practitioners only, using appropriate subdermal / deep dermal technique.

Related

Related collagen stimulators

Sculptra
Poly-L-Lactic Acid · Collagen Biostimulator
Rejubella
Polydioxanone Microspheres · Collagen Biostimulator
Ultra Ca+
Calcium Hydroxylapatite · Dual-Action Biostimulator
All Collagen Stimulators
Browse the full range.
Safety

Safety information

Radiesse is approved by the US FDA (PMA P050052) for aesthetic indications. This product is a collagen stimulator for licensed practitioners only. It must be prepared and injected at the appropriate depth using aseptic technique. Do not treat over active infection or inflammation, and avoid in pregnancy and breastfeeding or in patients with known hypersensitivity to the product components. As with all collagen biostimulators, delayed nodules or foreign-body reactions are possible; correct preparation, injection plane and technique help reduce this risk. Refer to the manufacturer’s instructions for use before treatment.

Radiesse is a trademark of its respective brand owner. For licensed healthcare professionals only. Last reviewed: June 2026.

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